Penicillin G Procaine + Dihydrostreptomycin Sulfate Suspension
Procaine penicillin G and Dihydrostreptomycin sulphate Injection (20:20)
COMPOSITION: Contains per ml: Procaine penicillin G ............ 200 000 IU. Dihydrostreptomycin sulphate.......200 000 IU. Solvents ad......................1ml.
CHARACTER:
The product is white or off-white injectable suspension
PHARMACOLOGICAL ACTION: The combination of procaine penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G is a smal spectrum penicillin with a bactericidal action against mainly Gram-positive bacteria like Campylobacter, Clostridium, Corynebacterium, Erysipelothrix, Haemophilus, Listeria, Pasteurella, penicillinase negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria like E. coli, Klebsiella, Pasteurella, Salmonella, and Staphylococcus spp.
INDICATIONS: Arthritis, mastitis and gastrointestinal, respiratory and urinary tract infections caused by penicillin and dihydrostreptomycin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Klebsiella, Listeria, Pasteurella, Salmonella, Staphylococcus, and Streptococcus spp., in calves, cattle, goats, sheep, and swin.
DOSAGE AND ADMINISTRATION: For intramuscular administration. Never intravenously. Shake well before use. Cattle, horses: 1 ml. per 20 kg. body weight daily for 3-5 days. Sheep, goats, and pigs : 1 ml. per 20 kg. body weight daily for 3-5 days. Young animals: Dosage 50% higher.
CONTRAINDICATIONS: - Hypersensitivity to penicillin, procaine and/or aminoglycosides. - Administration to animals with a serious impaired renal function. - Concurrent administration with tetracyclines, chloramphenicol, macrolides and lincosamides.
SIDE EFFECTS: - Administration of therapeutic dosages of procaine penicillin G can result in abortion in sows. - Ototoxity, neurotoxicity or nephrotoxicity. - Hypersensitivity reactions.
WITHDRAWAL TIME: - For kidney: 45 days. - For meat: 21 days. - For milk: 3 days.
WARNING: Keep out of reach of children.
RECOMMENDED SHELF LIFE: 3 years.
STORAGE: Store in cool places (max 25ºC). Do not expose to light.