Oxytetracycline HCl Injection 5% 100ml
Oxytetracycline HCl Injection 5%
PHARMACOLOGY:
Oxy is primarily bacteriostatic and is thought to exert its antimicrobial effect by the inhibition of protein synthesis. Oxy is active against a wide range of gram-negative and gram-positive organisms. The drugs in the tetracycline class have closely similar antimicrobial spectra and cross resistance among them is common. Micro-organisms may be considered susceptible of the M. I. C. (Minimum inhibitory concentration) is not more than 4.0 mcg/ml and intermediate if the M. I. C. Is 4.0 to 12.5mcg/ml.
PHARMACOKINETICS:
Oxy are readily absorbed and are bound to plasma proteins in varying degree. They are concentrated by the liver in the bile and excreted in the urine and faeces at high concentrations and in a biologically active form. Oxy is the least lipid soluble derivative among tetracycline class.
INDICATIONS:
Oxy is indicated in infections caused by the following micro-organisms. Rickettsiae (rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsial pox and tick fevers). Mycoplasma pneumoniae agents of psittacosis and ornithosis agents of lymphogranuloma venereum and granuloma inguinale; The spirochaetal agent of relapsing fever (Borrelia recurrentis).
CONTRAINDICATIONS:
The drug is contraindicated in animals who have shown hypersensitivity to any of the tetracyclines.
DOSAGE AND ADMINISTRATION:
Deep Intramuscular Injections:
Cattle, Horse, Camel, Sheep, Goat, Pig:
10mg-20mg per kg body weight
WITHDRAWAL PERIOD:
Meat: 7 days
Milk: 28 days
