cstp@cstpharm.com
+86 311 87250859

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cstp@cstpharm.com

+86 311 87250859

No. 25 Huangguan Road, Xinzhaidian Industrial Zone, Zhao Xian, Hebei Province, China

Oxy Injection 5% 100ml

Product Description

The product is for cattle, camels, and goats, and so on.


PHARMACOLOGY:
Oxy is primarily bacteriostatic and is thought to exert its antimicrobial effect by the inhibition of protein synthesis. Oxy is active against a wide range of gram-negative and gram-positive organisms. The drugs in the tetracycline class have closely similar antimicrobial spectra and cross resistance among them is common. Micro-organisms may be considered susceptible of the M. I. C. (Minimum inhibitory concentration) is not more than 4.0 mcg/ml and intermediate if the M. I. C. Is 4.0 to 12.5mcg/ml.

PHARMACOKINETICS:
Oxy are readily absorbed and are bound to plasma proteins in varying degree. They are concentrated by the liver in the bile and excreted in the urine and faeces at high concentrations and in a biologically active form. Oxy is the least lipid soluble derivative among tetracycline class.

INDICATIONS:
Oxy is indicated in infections caused by the following micro-organisms. Rickettsiae (rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsial pox and tick fevers). Mycoplasma pneumoniae agents of psittacosis and ornithosis agents of lymphogranuloma venereum and granuloma inguinale; The spirochaetal agent of relapsing fever (Borrelia recurrentis).

CONTRAINDICATIONS:
The drug is contraindicated in animals who have shown hypersensitivity to any of the tetracyclines.

WARNING:
Animal studies indicate that oxytetracycline crosses the placenta and found in fetal tissues and can have toxic effects on the developing foetus (often related to retardation of skeletal development)
Evidence of embryotoxicity has also been noted in animals treated early in pregnancy. The usage of Oxy during tooth development (last half of pregnancy, infancy) may cause permanent discolouration of teeth (Yellow-Grey-Brown). Therefore should not be used in this age group unless other drugs are not likely to be effective or are contraindicated. Oxy are present in the milk of lactating animal who are taking this drug.

PRECAUTIONS:
Oxy intramuscular solution should be injected well within the body of a relatively large muscle. As with all intramuscular injections aspiration is necessary to help avoid inadvertent injection into a blood vessel. If any super infection occurs the oxy should be discontinued and appropriate therapy instituted. Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, It is advisable to avoid giving tetracycline drugs in conjunction with penicillin.

DOSAGE AND ADMINISTRATION:
Deep Intramuscular Injections:
Cattle, Horse, Camel, Sheep, Goat, Pig:
10mg-20mg per kg body weight

WITHDRAWAL PERIOD:
Meat: 7 days
Milk: 28 days

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